Liver Transplant:Changing Lives
At Liver Treatment in India

Common Liver Diseases

The liver is one of the most vital organs in the human body, performing essential functions such as detoxification, protein synthesis, and the production of biochemicals necessary for digestion. However, it is also susceptible to various diseases that can significantly impact overall health. This article provides a comprehensive overview of common liver diseases, including hepatitis, cirrhosis, fatty liver disease, and liver cancer. We will explore the causes, symptoms, and risk factors associated with each condition, as well as their potential impact on liver function.

Hepatitis, an inflammation of the liver usually caused by viral infections, affects millions worldwide, while cirrhosis represents the advanced scarring of the liver typically resulting from long-term damage. Non-alcoholic fatty liver disease (NAFLD) has surged in prevalence, often linked to obesity and metabolic disorders. Lastly, liver cancer can arise as a consequence of chronic liver diseases, emphasizing the importance of early detection and timely intervention. By raising awareness of these conditions, we aim to empower individuals to take proactive steps towards liver health, including lifestyle modifications and regular screenings. Understanding the common liver diseases is crucial for prevention and effective management, ensuring that this essential organ remains healthy and functional.

1. Fatty Liver Disease

  • Non-alcoholic fatty liver disease (NAFLD): It is caused by fat accumulation in the liver that is unrelated to alcohol consumption. Obesity, diabetes, and high cholesterol are all common conditions.
  • Alcoholic Fatty Liver Disease: Caused by excessive alcohol consumption, which leads to fat deposition in liver cells.

Symptoms:

  • Initially, there may be no symptoms.
  • Fatigue, stomach discomfort, or slight liver enlargement.

Treatment:

  • It involves lifestyle adjustments such as healthy eating, regular exercise, and weight loss.
  • Abstinence from alcohol is essential for the treatment of alcoholic fatty liver.

2. Hepatitis

  • Hepatitis A, B, C, D, and E: Infections caused by various viruses, with Hepatitis B and C being the most serious and potentially chronic.
  • Autoimmune Hepatitis: In which the immune system destroys liver cells.

Symptoms:

  • It includes jaundice (yellowing of the skin and eyes).
  • Fever, nausea, vomiting, and stomach pain.
  • Chronic cases can develop into cirrhosis or liver cancer.

Treatment:

  • It includes antiviral medicines for Hepatitis B and C.
  • Vaccines for Hepatitis A and B prevention.
  • Immunosuppressive medications for autoimmune hepatitis.

3. Cirrhosis

Cirrhosis is the result of chronic liver injury, in which scar tissue replaces healthy liver cells, decreasing liver function.

Cause:

  • Chronic alcoholism.
  • Hepatitis B or C.
  • Nonalcoholic fatty liver disease.

Symptoms:

  • It includes weakness, weariness, and loss of appetite.
  • Easy bruising and bleeding.
  • Edema or ascites is swelling of the legs or abdomen.

Treatment:

  • It involves addressing the underlying cause (e.g., stopping drinking or treating hepatitis).
  • Medications to relieve symptoms such as edema.
  • In severe situations, liver transplantation may be required.

4. Liver Cancer

Hepatocellular carcinoma (HCC) is the most prevalent type of liver cancer, and it is commonly associated with chronic liver disorders such as hepatitis or cirrhosis.

Symptoms:

  • It includes unexplained weight loss.
  • Abdominal swelling or pain.
  • Jaundice and tiredness.

Treatment:

  • Options include surgical excision of the tumor or liver transplantation.
  • Advanced stages may require targeted medicines, chemotherapy, or immunotherapy.

5. Liver Infections and Abscesses

Bacterial or parasitic abscesses are caused by dangerous germs infecting liver tissue.

Symptoms:

  • It includes high temperature and chills.
  • Right upper abdominal ache.
  • Nausea and vomiting.

Treatment:

  • It involves using antibiotics or antifungal drugs to treat the infection.
  • Drainage of abscesses in extreme situations.

6. Hemochromatosis

Hemochromatosis is a hereditary disorder in which the body accumulates extra iron, causing damage to the liver and other organs.

Symptoms:

  • It includes joint discomfort and chronic weariness.
  • Darkened skin or diabetes in its later stages.
  • Liver hypertrophy or malfunction.

Treatment:

  • It involves regular blood removal (phlebotomy) to lower iron levels.
  • Avoid iron-rich foods and supplements.

7. Wilson’s Disease

A rare hereditary condition that causes copper to accumulate in the liver, brain, and other tissues.

Symptoms:

  • It include tremors, muscle rigidity, and difficulties speaking.
  • Jaundice and stomach ache.
  • Kayser-Fleischer rings refer to copper deposits in the eyes.

Treatment:

  • Medications for removing excess copper.
  • Dietary measures to reduce copper intake.

8. Primary Biliary Cholangitis (PBC)

An autoimmune disorder in which the bile ducts in the liver are gradually damaged, resulting in bile accumulation and liver damage.

Symptoms:

  • It includes itching (pruritis) and dry eyes/mouth.
  • Fatigue and stomach ache.
  • Jaundice in advanced stages.

Treatment:

  • Ursodeoxycholic acid can enhance bile flow.
  • Immunosuppressants help to regulate inflammation.

9. Liver Failure

Liver failure occurs when the liver loses all function, either suddenly (acute liver failure) or gradually (chronic liver failure).

Causes:

  • It includes viral hepatitis, heavy alcohol use, or medication toxicity (e.g., acetaminophen overdose).
  • Chronic liver disease or autoimmune diseases.

Symptoms:

  • It includes confusion, edema, jaundice, and gastrointestinal bleeding.
  • In acute situations, symptoms emerge quickly.

Treatment:

  • It involves addressing the underlying cause.
  • Supportive care in an intensive care unit (ICU).
  • Liver transplantation is reserved for irreversible conditions.

How Do You Prevent Liver Disorders?

  • Maintain a Healthy Weight: To avoid obesity-related liver disorders, eat a balanced diet and stay active.
  • Avoid Excess Alcohol: Moderation is essential for preventing alcoholic liver damage.
  • Practice Safe cleanliness: Avoid hepatitis infections by maintaining good cleanliness and using safe sex.
  • Vaccinations: Get your Hepatitis A and B vaccines on schedule.
  • Regular Health Screening: Early diagnosis of liver problems, via blood tests or imaging, can help avert consequences.